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Integrative molecular analyses define correlates of high B7-H3 expression in metastatic castrate-resistant prostate cancer
B7-H3 (CD276) is an immune checkpoint overexpressed in prostate cancer with minimal expression in normal tissues and associated with poor prognosis, making it an excellent therapy target. We interrogated B7-H3 expression and its regulation in metastatic castration-resistant prostate cancer (mCRPC)....
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630314/ https://www.ncbi.nlm.nih.gov/pubmed/36323882 http://dx.doi.org/10.1038/s41698-022-00323-2 |