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Tempo: an unsupervised Bayesian algorithm for circadian phase inference in single-cell transcriptomics
The circadian clock is a 24 h cellular timekeeping mechanism that regulates human physiology. Answering several fundamental questions in circadian biology will require joint measures of single-cell circadian phases and transcriptomes. However, no widespread experimental approaches exist for this pur...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630322/ https://www.ncbi.nlm.nih.gov/pubmed/36323668 http://dx.doi.org/10.1038/s41467-022-34185-w |