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Immune cells transcriptome-based drug repositioning for multiple sclerosis

OBJECTIVE: Finding target genes and target pathways of existing drugs for drug repositioning in multiple sclerosis (MS) based on transcriptomic changes in MS immune cells. MATERIALS AND METHODS: Based on transcriptome data from Gene Expression Omnibus (GEO) database, differentially expressed genes (...

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Detalles Bibliográficos
Autores principales: Yin, Xinyue, Rang, Xinming, Hong, Xiangxiang, Zhou, Yinglian, Xu, Chaohan, Fu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630342/
https://www.ncbi.nlm.nih.gov/pubmed/36341423
http://dx.doi.org/10.3389/fimmu.2022.1020721