HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes

AIM: Adult mammalian cardiomyocytes are incapable of significant proliferation, limiting regeneration after myocardial injury. Overexpression of the transcription factor Myc has been shown to drive proliferation in the adult mouse heart, but only when combined with Cyclin T1. As constitutive HRas ac...

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Detalles Bibliográficos
Autores principales: Boikova, Aleksandra, Bywater, Megan J., Quaife-Ryan, Gregory A., Straube, Jasmin, Thompson, Lucy, Ascanelli, Camilla, Littlewood, Trevor D., Evan, Gerard I., Hudson, James E., Wilson, Catherine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630352/
https://www.ncbi.nlm.nih.gov/pubmed/36337898
http://dx.doi.org/10.3389/fcvm.2022.948281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630352/
https://www.ncbi.nlm.nih.gov/pubmed/36337898
http://dx.doi.org/10.3389/fcvm.2022.948281

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