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Long-term microglia depletion impairs synapse elimination and auditory brainstem function

Specialized sound localization circuit development requires synapse strengthening, refinement, and pruning. Many of these functions are carried out by microglia, immune cells that aid in regulating neurogenesis, synaptogenesis, apoptosis, and synaptic removal. We previously showed that postnatal tre...

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Detalles Bibliográficos
Autores principales: Chokr, Sima M., Milinkeviciute, Giedre, Jimenez, Gisselle A., Abubakr, Hakeem, Cramer, Karina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630367/
https://www.ncbi.nlm.nih.gov/pubmed/36323869
http://dx.doi.org/10.1038/s41598-022-23250-5