MicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway

The microRNA (miR) miR-874, a potential tumour suppressor, causes cell death via target gene suppression in various cancer types. Mevalonate pathway inhibition also causes cell death in breast cancer. However, the relationship between the mevalonate pathway and miR-874-induced apoptosis or its assoc...

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Detalles Bibliográficos
Autores principales: Aersilan, Alimasi, Hashimoto, Naoko, Yamagata, Kazuyuki, Yokoyama, Masataka, Nakayama, Akitoshi, Shi, Xiaoyan, Nagano, Hidekazu, Sakuma, Ikki, Nohata, Nijiro, Kinoshita, Takashi, Seki, Naohiko, Rahmutulla, Bahityar, Kaneda, Atsushi, Zhahara, Siti Nurul, Gong, Yingbo, Nishimura, Motoi, Kawauchi, Shoichiro, Kawakami, Eiryo, Tanaka, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630378/
https://www.ncbi.nlm.nih.gov/pubmed/36323841
http://dx.doi.org/10.1038/s41598-022-23205-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630378/
https://www.ncbi.nlm.nih.gov/pubmed/36323841
http://dx.doi.org/10.1038/s41598-022-23205-w

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