TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT(1A) receptor agonist SEP-363856

SEP-363856 (SEP-856) is a novel antipsychotic under clinical development. It displays a unique pattern of receptor interaction, with only weak (partial agonist) activity at dopamine D(2) receptors, yet more potent agonist activity at the trace amine associated receptor (TAAR1) and 5-hydroxytryptamin...

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Detalles Bibliográficos
Autores principales: Saarinen, Marcus, Mantas, Ioannis, Flais, Ivana, Ågren, Richard, Sahlholm, Kristoffer, Millan, Mark J., Svenningsson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630386/
https://www.ncbi.nlm.nih.gov/pubmed/36100653
http://dx.doi.org/10.1038/s41386-022-01421-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630386/
https://www.ncbi.nlm.nih.gov/pubmed/36100653
http://dx.doi.org/10.1038/s41386-022-01421-2

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