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Parallel functional annotation of cancer-associated missense mutations in histone methyltransferases
Using exome sequencing for biomarker discovery and precision medicine requires connecting nucleotide-level variation with functional changes in encoded proteins. However, for functionally annotating the thousands of cancer-associated missense mutations, or variants of uncertain significance (VUS), p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630446/ https://www.ncbi.nlm.nih.gov/pubmed/36323913 http://dx.doi.org/10.1038/s41598-022-23229-2 |