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Vexed mutations promote degeneration of dopaminergic neurons through excessive activation of the innate immune response
The hallmark of Parkinson’s disease (PD) is the loss of dopaminergic (DA) neurons in the brain. However, little is known about why DA neurons are selectively vulnerable to PD. We previously completed a screen identifying genes associated with the progressive degeneration of DA neurons. Here we descr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630459/ https://www.ncbi.nlm.nih.gov/pubmed/36323700 http://dx.doi.org/10.1038/s41531-022-00417-5 |