Ras inhibitors gate chemoattractant concentration range for chemotaxis through controlling GPCR-mediated adaptation and cell sensitivity

Chemotaxis plays an essential role in recruitment of leukocytes to sites of inflammation. Eukaryotic cells sense chemoattractant with G protein-coupled receptors (GPCRs) and chemotax toward gradients with an enormous concentration range through adaptation. Cells in adaptation no longer respond to th...

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Detalles Bibliográficos
Autores principales: Xu, Xuehua, Jin, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630474/
https://www.ncbi.nlm.nih.gov/pubmed/36341344
http://dx.doi.org/10.3389/fimmu.2022.1020117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630474/
https://www.ncbi.nlm.nih.gov/pubmed/36341344
http://dx.doi.org/10.3389/fimmu.2022.1020117

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