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Radiotherapy delays malignant transformation and prolongs survival in patients with IDH-mutant gliomas

OBJECTIVE: IDH-mutant lower-grade gliomas (LGGs, grade 2 or 3) eventually transform into secondary grade 4 astrocytomas (sA(IDHmut/G4)). Here, we sought to describe the transformation time, risk factors, and outcomes in malignant transformation of IDH-mutant LGGs. METHODS: We screened data for 108 p...

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Detalles Bibliográficos
Autores principales: Liu, Yanwei, Chen, Huiyuan, Li, Guanzhang, Zhang, Jing, Yao, Kun, Wu, Chenxing, Li, Shouwei, Qiu, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630524/
https://www.ncbi.nlm.nih.gov/pubmed/36350001
http://dx.doi.org/10.20892/j.issn.2095-3941.2022.0472