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Involvement of endoplasmic reticulum stress in rifampicin-induced liver injury

Rifampicin is a first-line antituberculosis drug. Hepatocyte toxicity caused by rifampicin is a significant clinical problem. However, the specific mechanism by which rifampicin causes liver injury is still poorly understood. Endoplasmic reticulum (ER) stress can have both protective and proapoptoti...

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Detalles Bibliográficos
Autores principales: Hou, Wanqing, Nsengimana, Bernard, Yan, Chuyun, Nashan, Bjorn, Han, Shuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630567/
https://www.ncbi.nlm.nih.gov/pubmed/36339603
http://dx.doi.org/10.3389/fphar.2022.1022809