Preventing type 1 diabetes in late-stage pre-diabetic NOD mice with insulin: A central role for alum as adjuvant

BACKGROUND: Restoration of immune tolerance to disease-relevant antigens is an appealing approach to prevent or arrest an organ-specific autoimmune disease like type 1 diabetes (T1D). Numerous studies have identified insulin as a key antigen of interest to use in such strategies, but to date, the su...

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Detalles Bibliográficos
Autores principales: Martens, Pieter-Jan, Ellis, Darcy, Bruggeman, Ylke, Viaene, Marijke, Laureys, Jos, Teyton, Luc, Mathieu, Chantal, Gysemans, Conny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630573/
https://www.ncbi.nlm.nih.gov/pubmed/36339431
http://dx.doi.org/10.3389/fendo.2022.1023264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630573/
https://www.ncbi.nlm.nih.gov/pubmed/36339431
http://dx.doi.org/10.3389/fendo.2022.1023264

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