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Hypoxia inducible factor-1α mediates the mechanism of the Hedgehog pathway in tendinopathy repair by Asperosaponin VI

BACKGROUND: Our previous study found that asperosaponin VI (ASA VI) has a positive effect on the repair of tendinopathy. However, its molecular biological mechanism is unclear. OBJECTIVE: To investigate the role of hypoxia inducible factor-1α (HIF-1α) in mediating the hedgehog (Hh) pathway in tendin...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Cheng, Liang, He, Benxiang, Tan, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630612/
https://www.ncbi.nlm.nih.gov/pubmed/36382134
http://dx.doi.org/10.1016/j.reth.2022.10.008