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Anticancer Activity of ST101, A Novel Antagonist of CCAAT/Enhancer Binding Protein β

CCAAT/enhancer binding protein β (C/EBPβ) is a basic leucine zipper (bZIP) family transcription factor, which is upregulated or overactivated in many cancers, resulting in a gene expression profile that drives oncogenesis. C/EBPβ dimerization regulates binding to DNA at the canonical TTGCGCAA motif...

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Detalles Bibliográficos
Autores principales: Darvishi, Emad, Ghamsari, Lila, Leong, Siok F., Ramirez, Ricardo, Koester, Mark, Gallagher, Erin, Yu, Miao, Mason, Jody M., Merutka, Gene, Kappel, Barry J., Rotolo, Jim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630826/
https://www.ncbi.nlm.nih.gov/pubmed/36121385
http://dx.doi.org/10.1158/1535-7163.MCT-21-0962