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The genetics of myelodysplastic syndromes and the opportunities for tailored treatments

Genomic instability, microenvironmental aberrations, and somatic mutations contribute to the phenotype of myelodysplastic syndrome and the risk for transformation to AML. Genes involved in RNA splicing, DNA methylation, histone modification, the cohesin complex, transcription, DNA damage response pa...

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Detalles Bibliográficos
Autores principales: Kontandreopoulou, Christina-Nefeli, Kalopisis, Konstantinos, Viniou, Nora-Athina, Diamantopoulos, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630842/
https://www.ncbi.nlm.nih.gov/pubmed/36338673
http://dx.doi.org/10.3389/fonc.2022.989483