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Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
Type I interferons (IFNs) are essential innate immune proteins that maintain tissue homeostasis through tonic expression and can be upregulated to drive antiviral resistance and inflammation upon stimulation. However, the mechanisms that inhibit aberrant IFN upregulation in homeostasis and the impac...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630927/ https://www.ncbi.nlm.nih.gov/pubmed/36198273 http://dx.doi.org/10.1016/j.celrep.2022.111434 |