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Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation

Type I interferons (IFNs) are essential innate immune proteins that maintain tissue homeostasis through tonic expression and can be upregulated to drive antiviral resistance and inflammation upon stimulation. However, the mechanisms that inhibit aberrant IFN upregulation in homeostasis and the impac...

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Detalles Bibliográficos
Autores principales: Wang, Yaqiu, Karki, Rajendra, Mall, Raghvendra, Sharma, Bhesh Raj, Kalathur, Ravi C., Lee, SangJoon, Kancharana, Balabhaskararao, So, Matthew, Combs, Katie L., Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630927/
https://www.ncbi.nlm.nih.gov/pubmed/36198273
http://dx.doi.org/10.1016/j.celrep.2022.111434