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Somatic mutations in FAT cadherin family members constitute an underrecognized subtype of colorectal adenocarcinoma with unique clinicopathologic features

BACKGROUND: The FAT cadherin family members (FAT1, FAT2, FAT3 and FAT4) are conserved tumor suppressors that are recurrently mutated in several types of human cancers, including colorectal carcinoma (CRC). AIM: To characterize the clinicopathologic features of CRC patients with somatic mutations in...

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Detalles Bibliográficos
Autores principales: Wang, Liang-Li, Zheng, Wei, Liu, Xiu-Li, Yin, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9630991/
https://www.ncbi.nlm.nih.gov/pubmed/36337316
http://dx.doi.org/10.5306/wjco.v13.i10.779