Synthetic Retinoid Kills Drug‐Resistant Cancer Stem Cells via Inducing RARγ‐Translocation‐Mediated Tension Reduction and Chromatin Decondensation

A recently developed synthetic retinoid abrogates proliferation and induces apoptosis of drug‐resistant malignant‐cancer‐stem‐cell‐like cells. However, the underlying mechanisms of how the synthetic retinoid induces cancer‐stem‐cell‐like cell tumor‐repopulating cell (TRC) apoptosis are elusive. Here...

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Detalles Bibliográficos
Autores principales: Zhang, Yao, Dong, Qi, An, Quanlin, Zhang, Chumei, Mohagheghian, Erfan, Niu, Bing, Qi, Feng, Wei, Fuxiang, Chen, Sihan, Chen, Xinman, Wang, Anqi, Cao, Xin, Wang, Ning, Chen, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631059/
https://www.ncbi.nlm.nih.gov/pubmed/36031407
http://dx.doi.org/10.1002/advs.202203173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631059/
https://www.ncbi.nlm.nih.gov/pubmed/36031407
http://dx.doi.org/10.1002/advs.202203173

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