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A critical developmental window for ELAV/Hu-dependent mRNA signatures at the onset of neuronal differentiation

Cell-type-specific gene regulatory programs are essential for cell differentiation and function. In animal neurons, the highly conserved ELAV/Hu family of proteins promotes alternative splicing and polyadenylation of mRNA precursors to create unique neuronal transcript isoforms. Here, we assess tran...

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Detalles Bibliográficos
Autores principales: Carrasco, Judit, Mateos, Fernando, Hilgers, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631114/
https://www.ncbi.nlm.nih.gov/pubmed/36288718
http://dx.doi.org/10.1016/j.celrep.2022.111542