Genotype-phenotype association and biochemical analyses of glucose-6-phosphate dehydrogenase variants: Implications for the hemolytic risk of using 8-aminoquinolines for radical cure

Background: Plasmodium vivax remains the malaria species posing a major threat to human health worldwide owing to its relapse mechanism. Currently, the only drugs of choice for radical cure are the 8-aminoquinolines (primaquine and tafenoquine), which are capable of killing hypnozoites and thus prev...

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Detalles Bibliográficos
Autores principales: Sudsumrit, Sirapapha, Chamchoy, Kamonwan, Songdej, Duantida, Adisakwattana, Poom, Krudsood, Srivicha, Adams, Emily R., Imwong, Mallika, Leartsakulpanich, Ubolsree, Boonyuen, Usa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631214/
https://www.ncbi.nlm.nih.gov/pubmed/36339627
http://dx.doi.org/10.3389/fphar.2022.1032938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631214/
https://www.ncbi.nlm.nih.gov/pubmed/36339627
http://dx.doi.org/10.3389/fphar.2022.1032938

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