IFNγ regulates NAD(+) metabolism to promote the respiratory burst in human monocytes

Interferon γ (IFNγ) is an essential and pleiotropic activator of human monocytes, but little is known about the changes in cellular metabolism required for IFNγ-induced activation. We sought to elucidate the mechanisms by which IFNγ reprograms monocyte metabolism to support its immunologic activitie...

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Detalles Bibliográficos
Autores principales: McCann, Katelyn J., Christensen, Stephen M., Colby, Devon H., McGuire, Peter J., Myles, Ian A., Zerbe, Christa S., Dalgard, Clifton L., Sukumar, Gauthaman, Leonard, Warren J., McCormick, Beth A., Holland, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631555/
https://www.ncbi.nlm.nih.gov/pubmed/35500221
http://dx.doi.org/10.1182/bloodadvances.2021005776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631555/
https://www.ncbi.nlm.nih.gov/pubmed/35500221
http://dx.doi.org/10.1182/bloodadvances.2021005776

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