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Alterations in B- and circulating T-follicular helper cell subsets in immune thrombotic thrombocytopenic purpura

T follicular helper (Tfh) cells regulate development of antigen-specific B-cell immunity. We prospectively investigated B-cell and circulating Tfh (cTfh) cell subsets in 45 patients with immune thrombotic thrombocytopenic purpura (iTTP) at presentation and longitudinally after rituximab (RTX). B-cel...

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Detalles Bibliográficos
Autores principales: Shin, Jin-Sup, Subhan, Maryam Owais, Cambridge, Geraldine, Guo, Yanping, de Groot, Rens, Scully, Marie, Thomas, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631570/
https://www.ncbi.nlm.nih.gov/pubmed/35507753
http://dx.doi.org/10.1182/bloodadvances.2022007025