CPT2 K79 acetylation regulates platelet life span

The short life span of platelets is a major challenge to platelet transfusion services because of the lack of effective intervention. Here, we found that the accumulation of long-chain acylcarnitines (LCACs) is responsible for mitochondrial damage and platelet storage lesion. Further studies showed...

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Detalles Bibliográficos
Autores principales: Fan, Xuemei, Wang, Yang, Cai, Xiaohong, Shen, Yingzhi, Xu, Tongran, Xu, Yanyan, Cheng, Jinke, Wang, Xuefeng, Zhang, Lin, Dai, Jing, Lin, Shuhai, Liu, Junling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631617/
https://www.ncbi.nlm.nih.gov/pubmed/35728063
http://dx.doi.org/10.1182/bloodadvances.2021006687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631617/
https://www.ncbi.nlm.nih.gov/pubmed/35728063
http://dx.doi.org/10.1182/bloodadvances.2021006687

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