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Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice
Megakaryocytes are large cells in the bone marrow that give rise to blood platelets. Platelet biogenesis involves megakaryocyte maturation, the localization of the mature cells in close proximity to bone marrow sinusoids, and the formation of protrusions, which are elongated and shed within the circ...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631634/ https://www.ncbi.nlm.nih.gov/pubmed/35819450 http://dx.doi.org/10.1182/bloodadvances.2021006545 |