Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice

Megakaryocytes are large cells in the bone marrow that give rise to blood platelets. Platelet biogenesis involves megakaryocyte maturation, the localization of the mature cells in close proximity to bone marrow sinusoids, and the formation of protrusions, which are elongated and shed within the circ...

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Detalles Bibliográficos
Autores principales: Englert, Maximilian, Aurbach, Katja, Becker, Isabelle C., Gerber, Annika, Heib, Tobias, Wackerbarth, Lou M., Kusch, Charly, Mott, Kristina, Araujo, Gabriel H. M., Baig, Ayesha A., Dütting, Sebastian, Knaus, Ulla G., Stigloher, Christian, Schulze, Harald, Nieswandt, Bernhard, Pleines, Irina, Nagy, Zoltan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631634/
https://www.ncbi.nlm.nih.gov/pubmed/35819450
http://dx.doi.org/10.1182/bloodadvances.2021006545

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