Dominant epitopes presented by prevalent HLA alleles permit wide use of banked CMVpp65 T cells in adoptive therapy

We established and characterized a bank of 138 CMVpp65 peptide-specific T-cell (CMVpp65CTLs) lines from healthy marrow transplant donors who consented to their use for treatment of individuals other than their transplant recipient. CMVpp65CTL lines included 131 containing predominantly CD8(+) T cell...

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Detalles Bibliográficos
Autores principales: Hasan, Aisha N., Doubrovina, Ekaterina, Sottile, Rosa, Prockop, Susan, Klatt, Martin G., Heller, Glenn, Selvakumar, Annamalai, Barnett, Lorna, Hsu, Katharine C., O’Reilly, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631666/
https://www.ncbi.nlm.nih.gov/pubmed/35605246
http://dx.doi.org/10.1182/bloodadvances.2022007005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631666/
https://www.ncbi.nlm.nih.gov/pubmed/35605246
http://dx.doi.org/10.1182/bloodadvances.2022007005

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