Upregulated SPAG6 promotes acute myeloid leukemia progression through MYO1D that regulates the EGFR family expression

Chromosomal aberrations and gene mutations have been considered to be the major reasons for high recurrence rates and poor survival among acute myeloid leukemia (AML) patients. However, the underlying molecular mechanism of AML gene mutation remains largely unclear. Here, we show that SPAG6 (sperm-a...

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Detalles Bibliográficos
Autores principales: Mu, Jiao, Yuan, Peng, Luo, Jie, Chen, Yafan, Tian, Yiyuan, Ding, Li, Zhao, Beibei, Wang, Xiaocheng, Wang, Bao, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631693/
https://www.ncbi.nlm.nih.gov/pubmed/35667090
http://dx.doi.org/10.1182/bloodadvances.2021006920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631693/
https://www.ncbi.nlm.nih.gov/pubmed/35667090
http://dx.doi.org/10.1182/bloodadvances.2021006920

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