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Upregulated SPAG6 promotes acute myeloid leukemia progression through MYO1D that regulates the EGFR family expression
Chromosomal aberrations and gene mutations have been considered to be the major reasons for high recurrence rates and poor survival among acute myeloid leukemia (AML) patients. However, the underlying molecular mechanism of AML gene mutation remains largely unclear. Here, we show that SPAG6 (sperm-a...
Autores principales: | Mu, Jiao, Yuan, Peng, Luo, Jie, Chen, Yafan, Tian, Yiyuan, Ding, Li, Zhao, Beibei, Wang, Xiaocheng, Wang, Bao, Liu, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631693/ https://www.ncbi.nlm.nih.gov/pubmed/35667090 http://dx.doi.org/10.1182/bloodadvances.2021006920 |
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