Differential regulation of CTLA4 expression through BTK-dependent and independent mechanisms in CLL

Cytotoxic T lymphocyte antigen 4 (CTLA4) is a major immune checkpoint and target for cancer immunotherapy. Although originally discovered and primarily studied on T cells, its role on other cell types has also been recognized in recent years. Here we describe an unexpected interaction between ibruti...

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Detalles Bibliográficos
Autores principales: Yano, Max, Nunes, Jessica, Mo, Xiaokui, Rogers, Kerry A., Woyach, Jennifer A., Byrd, John C., Muthusamy, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631695/
https://www.ncbi.nlm.nih.gov/pubmed/35759759
http://dx.doi.org/10.1182/bloodadvances.2021005571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631695/
https://www.ncbi.nlm.nih.gov/pubmed/35759759
http://dx.doi.org/10.1182/bloodadvances.2021005571

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