Metabolic reprogramming under hypoxic storage preserves faster oxygen unloading from stored red blood cells

Stored red blood cells (RBCs) incur biochemical and morphological changes, collectively termed the storage lesion. Functionally, the storage lesion manifests as slower oxygen unloading from RBCs, which may compromise the efficacy of transfusions where the clinical imperative is to rapidly boost oxyg...

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Detalles Bibliográficos
Autores principales: Rabcuka, Julija, Blonski, Slawomir, Meli, Athinoula, Sowemimo-Coker, Samuel, Zaremba, Damian, Stephenson, Daniel, Dzieciatkowska, Monika, Nerguizian, David, Cardigan, Rebecca, Korczyk, Piotr M., Smethurst, Peter A., D’Alessandro, Angelo, Swietach, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Transfusion Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631703/
https://www.ncbi.nlm.nih.gov/pubmed/35736672
http://dx.doi.org/10.1182/bloodadvances.2022007774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631703/
https://www.ncbi.nlm.nih.gov/pubmed/35736672
http://dx.doi.org/10.1182/bloodadvances.2022007774

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