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Mechanistic Insight into the Binding of Huperzine a with Human Transferrin: Computational, Spectroscopic and Calorimetric Approaches

[Image: see text] Huperzine A (HupA), an alkaloid found in the club moss Huperzia Serrata, has been in use for centuries in Chinese traditional medicine to treat dementia owing to its ability to inhibit the cholinergic enzyme acetylcholinesterase (AChE), thus acting as an acetylcholinesterase inhibi...

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Detalles Bibliográficos
Autores principales: Atiya, Akhtar, Alhumaydhi, Fahad A., Shamsi, Anas, Olatunde, Ahmed, Alsagaby, Suliman A., Al Abdulmonem, Waleed, Sharaf, Sharaf E., Shahwan, Moyad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631745/
https://www.ncbi.nlm.nih.gov/pubmed/36340147
http://dx.doi.org/10.1021/acsomega.2c03185