Cargando…

Chimeric immune checkpoint protein vaccines inhibit the tumorigenesis and growth of rat cholangiocarcinoma

Cholangiocarcinoma (CCA) is the second most common primary liver malignancy and carries a dismal prognosis due to difficulties in achieving an optimal resection, and poor response to current standard-of-care systemic therapies. We previously devised a CTLA4-PD-L1 DNA cancer vaccine (DNA vaccine) and...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Yi-Ru, Wu, Chiao-En, Huang, Wen-Kuan, Chen, Ming-Huang, Lan, Keng-Hsueh, Yeh, Chun-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631822/
https://www.ncbi.nlm.nih.gov/pubmed/36341387
http://dx.doi.org/10.3389/fimmu.2022.982196