Closed-loop control of continuous piperacillin delivery: An in silico study

Background and objective: Sub-therapeutic dosing of piperacillin-tazobactam in critically-ill patients is associated with poor clinical outcomes and may promote the emergence of drug-resistant infections. In this paper, an in silico investigation of whether closed-loop control can improve pharmacoki...

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Detalles Bibliográficos
Autores principales: Herrero, Pau, Wilson, Richard C., Armiger, Ryan, Roberts, Jason A., Holmes, Alison, Georgiou, Pantelis, Rawson, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631830/
https://www.ncbi.nlm.nih.gov/pubmed/36338121
http://dx.doi.org/10.3389/fbioe.2022.1015389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631830/
https://www.ncbi.nlm.nih.gov/pubmed/36338121
http://dx.doi.org/10.3389/fbioe.2022.1015389

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