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Identification of cholinergic centro-cingulate topography as main contributor to cognitive functioning in Parkinson’s disease: Results from a data-driven approach

BACKGROUND: Degeneration of the cholinergic system plays an important role in cognitive impairment in Parkinson’s disease (PD). Positron emission tomography (PET) imaging using the presynaptic vesicular acetylcholine transporter (VAChT) tracer [(18)F]Fluoroethoxybenzovesamicol ([(18)F]FEOBV) allows...

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Detalles Bibliográficos
Autores principales: van der Zee, Sygrid, Kanel, Prabesh, Müller, Martijn L. T. M., van Laar, Teus, Bohnen, Nicolaas I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631831/
https://www.ncbi.nlm.nih.gov/pubmed/36337707
http://dx.doi.org/10.3389/fnagi.2022.1006567