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Sevoflurane exposure causes neuronal apoptosis and cognitive dysfunction by inducing ER stress via activation of the inositol 1, 4, 5-trisphosphate receptor

The role of the inositol 1, 4, 5-trisphosphate receptor (IP3R) in hippocampal neuronal apoptosis and cognitive dysfunction induced by sevoflurane is currently unclear. Therefore, in this study, we investigated the role of the IP3R in endoplasmic reticulum (ER) stress and hippocampal neuronal apoptos...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Li, Yanan, Wang, Xupeng, Yin, Chunping, Zhou, Qi, Guo, Junfei, Zhao, Juan, Xian, Xiaohui, Hou, Zhiyong, Wang, Qiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631943/
https://www.ncbi.nlm.nih.gov/pubmed/36337694
http://dx.doi.org/10.3389/fnagi.2022.990679