Cargando…

8-Oxoguanine Forms Quartets with a Large Central Cavity

[Image: see text] Oxidation of a guanine nucleotide in DNA yields an 8-oxoguanine nucleotide ((oxo)G) and is a mutagenic event in the genome. Due to different arrangements of hydrogen-bond donors and acceptors, (oxo)G can affect the secondary structure of nucleic acids. We have investigated base pai...

Descripción completa

Detalles Bibliográficos
Autores principales: Aleksič, Simon, Podbevšek, Peter, Plavec, Janez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631995/
https://www.ncbi.nlm.nih.gov/pubmed/36260746
http://dx.doi.org/10.1021/acs.biochem.2c00478