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GMMchi: gene expression clustering using Gaussian mixture modeling

BACKGROUND: Cancer evolution consists of a stepwise acquisition of genetic and epigenetic changes, which alter the gene expression profiles of cells in a particular tissue and result in phenotypic alterations acted upon by natural selection. The recurrent appearance of specific genetic lesions acros...

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Detalles Bibliográficos
Autores principales: Liu, Ta-Chun, Kalugin, Peter N., Wilding, Jennifer L., Bodmer, Walter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632092/
https://www.ncbi.nlm.nih.gov/pubmed/36324085
http://dx.doi.org/10.1186/s12859-022-05006-0