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Profile and Predictors of Blood Tumor Mutational Burden in Advanced Hepatocellular Carcinoma

Advanced hepatocellular carcinoma (HCC) is responsive to immune checkpoint inhibitors, but there are currently no known biomarkers to predict treatment benefit. Blood TMB (bTMB) estimation via circulating tumor DNA (ctDNA) profiling can provide a convenient means to estimate HCC TMB. Here we provide...

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Detalles Bibliográficos
Autores principales: Franses, Joseph W, Lim, Mir, Burgoyne, Adam M, Mody, Kabir, Lennerz, Jochen, Chang, Jeremy, Imperial, Robin, Dybel, Stacey N, Dinh, Thi M, Masannat, Jude, Weipert, Caroline M, Hsiehchen, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632309/
https://www.ncbi.nlm.nih.gov/pubmed/36103364
http://dx.doi.org/10.1093/oncolo/oyac189