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Antibiotic Exposure Does Not Impact Immune Checkpoint Blockade Response in MSI-H/dMMR Metastatic Colorectal Cancer: A Single-Center Experience

BACKGROUND: Immune checkpoint blockade (ICB) has improved outcomes for patients with microsatellite instability high (MSI-H)/deficient mismatch repair (dMMR) tumors. However, not all MSI-H/dMMR patients will exhibit the same ICB efficacy. Previous studies suggest that concomitant antibiotic use whil...

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Detalles Bibliográficos
Autores principales: Serpas Higbie, Victoria, Rogers, Jane, Hwang, Hyunsoo, Qiao, Wei, Xiao, Lianchun, Dasari, Arvind, Mola-Rudd, Kerri, Morris, Van K, Wolff, Robert A, Raghav, Kanwal, Huey, Ryan, Parseghian, Christine, Willis, Jason, Kopetz, Scott, Overman, Michael J, Johnson, Benny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632313/
https://www.ncbi.nlm.nih.gov/pubmed/35946836
http://dx.doi.org/10.1093/oncolo/oyac162