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Gain-of-function of TRPM4 predisposes mice to psoriasiform dermatitis
Transient receptor potential melastatin 4 (TRPM4) is a Ca(2+)-activated, monovalent cation channel that is expressed in a wide range of cells. We previously reported two gain-of-function (GoF) mutations of TRPM4 as the cause of progressive symmetric erythrokeratodermia (PSEK), which shares similar c...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632438/ https://www.ncbi.nlm.nih.gov/pubmed/36341417 http://dx.doi.org/10.3389/fimmu.2022.1025499 |