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Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants

Tuberculosis vaccine development is hindered by the lack of validated immune correlates of protection. Exploring immune correlates of risk of disease and/or infection in prospective samples can inform this field. We investigate whether previously identified immune correlates of risk of TB disease al...

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Detalles Bibliográficos
Autores principales: Satti, Iman, Wittenberg, Rachel E., Li, Shuailin, Harris, Stephanie A., Tanner, Rachel, Cizmeci, Deniz, Jacobs, Ashley, Williams, Nicola, Mulenga, Humphrey, Fletcher, Helen A., Scriba, Thomas J., Tameris, Michele, Hatherill, Mark, McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632577/
https://www.ncbi.nlm.nih.gov/pubmed/36329009
http://dx.doi.org/10.1038/s41467-022-34061-7