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The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis

Given the plasticity of hematopoietic stem and progenitor cells, multiple routes of differentiation must be blocked in the the pathogenesis of acute myeloid leukemia, the molecular basis of which is incompletely understood. We report that posttranscriptional repression of the transcription factor AR...

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Detalles Bibliográficos
Autores principales: Alejo-Valle, Oriol, Weigert, Karoline, Bhayadia, Raj, Ng, Michelle, Issa, Hasan, Beyer, Christoph, Emmrich, Stephan, Schuschel, Konstantin, Ihling, Christian, Sinz, Andrea, Zimmermann, Martin, Wickenhauser, Claudia, Flasinski, Marius, Regenyi, Eniko, Labuhn, Maurice, Reinhardt, Dirk, Yaspo, Marie-Laure, Heckl, Dirk, Klusmann, Jan-Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632760/
https://www.ncbi.nlm.nih.gov/pubmed/34570885
http://dx.doi.org/10.1182/blood.2021012231