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The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis
Given the plasticity of hematopoietic stem and progenitor cells, multiple routes of differentiation must be blocked in the the pathogenesis of acute myeloid leukemia, the molecular basis of which is incompletely understood. We report that posttranscriptional repression of the transcription factor AR...
Autores principales: | Alejo-Valle, Oriol, Weigert, Karoline, Bhayadia, Raj, Ng, Michelle, Issa, Hasan, Beyer, Christoph, Emmrich, Stephan, Schuschel, Konstantin, Ihling, Christian, Sinz, Andrea, Zimmermann, Martin, Wickenhauser, Claudia, Flasinski, Marius, Regenyi, Eniko, Labuhn, Maurice, Reinhardt, Dirk, Yaspo, Marie-Laure, Heckl, Dirk, Klusmann, Jan-Henning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632760/ https://www.ncbi.nlm.nih.gov/pubmed/34570885 http://dx.doi.org/10.1182/blood.2021012231 |
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