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SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by the World Health Organization (WHO). Early clinical symptomatology focused mainly on respiratory illnesses. However, a variety of n...

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Detalles Bibliográficos
Autores principales: Mesci, Pinar, de Souza, Janaina S., Martin-Sancho, Laura, Macia, Angela, Saleh, Aurian, Yin, Xin, Snethlage, Cedric, Adams, Jason W., Avansini, Simoni H., Herai, Roberto H., Almenar-Queralt, Angels, Pu, Yuan, Szeto, Ryan A., Goldberg, Gabriela, Bruck, Patrick T., Papes, Fabio, Chanda, Sumit K., Muotri, Alysson R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632769/
https://www.ncbi.nlm.nih.gov/pubmed/36327326
http://dx.doi.org/10.1371/journal.pbio.3001845