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COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection

Genome wide association studies show there is a genetic component to severe COVID-19. We find evidence that the genome-wide genetic association signal with severe COVID-19 is correlated with that of systemic lupus erythematosus (SLE), having formally tested this using genetic correlation analysis by...

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Detalles Bibliográficos
Autores principales: Wang, Yuxuan, Guga, Suri, Wu, Kejia, Khaw, Zoe, Tzoumkas, Konstantinos, Tombleson, Phil, Comeau, Mary E., Langefeld, Carl D., Cunninghame Graham, Deborah S., Morris, David L., Vyse, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632821/
https://www.ncbi.nlm.nih.gov/pubmed/36327221
http://dx.doi.org/10.1371/journal.pgen.1010253