Cargando…

Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis

Early lung cancer lesions develop within a unique microenvironment that undergoes constant cyclic stretch from respiration. While tumor stiffening is an established driver of tumor progression, the contribution of stress and strain to lung cancer is unknown. We developed tissue scale finite element...

Descripción completa

Detalles Bibliográficos
Autores principales: Zitnay, Rebecca G., Herron, Michael R., Carney, Keith R., Potter, Scott, Emerson, Lyska L., Weiss, Jeffrey A., Mendoza, Michelle C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632844/
https://www.ncbi.nlm.nih.gov/pubmed/36279309
http://dx.doi.org/10.1371/journal.pcbi.1010153