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Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis
Early lung cancer lesions develop within a unique microenvironment that undergoes constant cyclic stretch from respiration. While tumor stiffening is an established driver of tumor progression, the contribution of stress and strain to lung cancer is unknown. We developed tissue scale finite element...
Autores principales: | Zitnay, Rebecca G., Herron, Michael R., Carney, Keith R., Potter, Scott, Emerson, Lyska L., Weiss, Jeffrey A., Mendoza, Michelle C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632844/ https://www.ncbi.nlm.nih.gov/pubmed/36279309 http://dx.doi.org/10.1371/journal.pcbi.1010153 |
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