Cargando…
Phosphoinositide species and filamentous actin formation mediate engulfment by senescent tumor cells
Cancer cells survive chemotherapy and cause lethal relapse by entering a senescent state that facilitates expression of many phagocytosis/macrophage-related genes that engender a novel cannibalism phenotype. We used biosensors and live-cell imaging to reveal the basic steps and mechanisms of engulfm...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632905/ https://www.ncbi.nlm.nih.gov/pubmed/36279312 http://dx.doi.org/10.1371/journal.pbio.3001858 |