Intracellular acidification is a hallmark of thymineless death in E. coli

Thymidine starvation causes rapid cell death. This enigmatic process known as thymineless death (TLD) is the underlying killing mechanism of diverse antimicrobial and antineoplastic drugs. Despite decades of investigation, we still lack a mechanistic understanding of the causal sequence of events th...

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Detalles Bibliográficos
Autores principales: Ketcham, Alexandra, Freddolino, Peter L., Tavazoie, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632930/
https://www.ncbi.nlm.nih.gov/pubmed/36279294
http://dx.doi.org/10.1371/journal.pgen.1010456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632930/
https://www.ncbi.nlm.nih.gov/pubmed/36279294
http://dx.doi.org/10.1371/journal.pgen.1010456

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